Target | |
---|---|
Synonyms | BCM; TNFRSF17; CD269; TNFRSF13A |
Description | Recombinant Cynomolgus BCMA protein with C-terminal human Fc tag |
Delivery | In Stock |
Uniprot ID | XP_005591343.1 |
Expression Host | HEK293 |
Tag | C-Human Fc tag |
Molecular Characterization | BCMA(Met1-Asn52) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of cBCMA-hFc is approximately 25-55 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] |
Usage | Research use only |
Conjugate | Unconjugated |
Cynomolgus BCMA Protein, hFc Tag
Price: 10μg $100.00; 50μg $358.00 ; 100 μg $528.00
Product Data
Images
Figure 1. Cynomolgus BCMA Protein, hFc Tag on SDS-PAGE under reducing condition.
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