| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | 5HT3D |
| Description | Human 5HT3D full length protein-synthetic nanodisc |
| Delivery | 6~8weeks |
| Uniprot ID | Q70Z44 |
| Expression Host | HEK293 |
| Protein Families | Ion Channels: Cys-loop Receptors |
| Protein Pathways | N/A |
| Molecular Weight | The human full length 5HT3D protein has a MW of 50.2kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human 5HT3D full length protein-synthetic nanodisc
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Related Products
Full Length Transmembrane Proteins
SKU: FLP120782 Target: 5HT3D
Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00