Name: Human ABCG1 full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100156

Tag	C-Flag Tag
Target	ABCG1
Synonyms	ABC8; WHITE1
Description	Human ABCG1 full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	P45844
Expression Host	HEK293
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ABC transporters
Molecular Weight	The human full length ABCG1 protein has a MW of 75.6 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types
Usage	Research use only
Conjugate	Unconjugated

Human ABCG1 full length protein-synthetic nanodisc