| Target | |
|---|---|
| Synonyms | ACE-2;ACEH;ACE2 |
| Description | Recombinant Human ACE2 Protein with N-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | Q9BYF1 |
| Expression Host | HEK293 |
| Tag | N-6×His Tag |
| Molecular Characterization | 6×His ACE2(Gln18-Ser740) |
| Molecular Weight | The protein has a predicted molecular mass of 84.4 kDa after removal of the signal peptide. The apparent molecular mass of His-ACE2 is approximately 100-130 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human ACE2 Protein, His Tag
Price: 10μg $78.00; 50μg $310.00 ; 100 μg $460.00
Product Data
Images
Figure 1. Human ACE2 Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human ACE2, His Tagged protein（PME100490）can bind S-RBD, hFc tagged protein PME100487 in a linear range of 0.128-80.0 ng/ml.
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