Target | |
---|---|
Synonyms | ACKR3; CMKOR1; CXC-R7; CXCR-7; GPR159; RDC-1; RDC1 |
Description | Human CXCR7 full length protein-synthetic nanodisc |
Delivery | In Stock |
Uniprot ID | P25106 |
Expression Host | HEK293 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | N/A |
Molecular Weight | The human full length CXCR7 protein has a MW of 41.5 kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | A member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. |
Usage | Research use only |
Human CXCR7 full length protein-synthetic nanodisc
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were pre-coated with Flag Tag CXCR7-Nanodisc (0.2μg/per well). Serial diluted anti-CXCR7 monoclonal antibody (DMC100443) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CXCR7 monoclonal antibody binding with CXCR7-Nanodisc is 14.28ng/ml.
Figure2. Human CXCR7-Nanodisc, Flag Tag on SDS-PAGE