Name: Human ADGRD1-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120127

Tag	C-Flag&Strep Tag
Target	ADGRD1
Synonyms	GPR133; PGR25
Description	Human ADGRD1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q6QNK2
Expression Host	HEK293
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length ADGRD1-Strep protein has a MW of 96.5 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.
Usage	Research use only
Conjugate	Unconjugated

Human ADGRD1-Strep full length protein-synthetic nanodisc