Target | |
---|---|
Synonyms | ANGPT2;GPT2;NG2;ngiopoietin-2 |
Description | Recombinant human ANGPT2 protein with C-terminal human Fc tag |
Delivery | Under development |
Uniprot ID | O15123 |
Expression Host | HEK293 |
Tag | C-Human Fc Tag |
Molecular Characterization | ANGPT2(Lys275-Phe496) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 49.94 kDa after removal of the signal peptide. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. |
Usage | Research use only |
Conjugate | Unconjugated |
Human ANGPT2 Protein, hFc Tag
Price: 10μg $72.00; 50μg $274.00 ; 100 μg $411.00
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