Target | |
---|---|
Synonyms | APJ; APJR; HG11; AGTRL1 |
Description | Recombinant human APLNR Protein with C-terminal human Fc tag |
Delivery | In Stock |
Uniprot ID | P35414 |
Expression Host | HEK293 |
Tag | C-Human Fc tag |
Molecular Characterization | APLNR(Met1-Ser26) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 29.2 kDa after removal of the signal peptide. The apparent molecular mass of APLNR-hFc is approximately 35-55 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009] |
Usage | Research use only |
Conjugate | Unconjugated |
Human APLNR Protein, hFc Tag
Price: 10μg $90.00; 50μg $320.00 ; 100 μg $480.00
Product Data
Images
Figure 1. Human APLNR Protein, hFc Tag on SDS-PAGE under reducing condition.
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