Target | |
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Synonyms | C-C Motif Chemokine 5;EoCP;Eosinophil Chemotactic Cytokine;SIS-Delta;Small-Inducible Cytokine A5;T Cell-Specific Protein P228;TCP228;T-Cell-Specific Protein RANTES;CCL5;D17S136E;SCYA5 |
Description | Recombinant Human C-C Motif Chemokine 5 is produced by our E.coli expression system and the target gene encoding Ser24-Ser91 is expressed. |
Delivery | In Stock |
Uniprot ID | P13501 |
Expression Host | E.coli |
Tag | |
Molecular Characterization | Not available |
Molecular Weight | 7.8 KDa |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases. |
Usage | Research use only |
Conjugate | Unconjugated |
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
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