| Target | |
|---|---|
| Synonyms | CEACAM-5;CD66e;CEA;Meconium antigen 100 |
| Description | Recombinant human CEACAM5 protein with C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | P06731 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | CEACAM5(Lys35-Ala685) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 72.2 kDa after removal of the signal peptide. The apparent molecular mass of CEACAM5-His is approximately 100-130 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CEACAM5 Protein, His Tag
Price: 10μg $82.00; 50μg $320.00 ; 100 μg $480.00
Product Data
Images
Figure 1. Human CEACAM5 Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CEACAM5, His tagged protein (PME100071) can bind Anti-CEACAM5 Antibody (BME100035) in a linear range of 2.56-320 ng/ml.
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CEACAM5 Protein, His Tag (PME100071) can bind Anti-CEACAM5(tusamitamab biosimilar) mAb (BME100195) in a linear range of 0.64–16 ng/mL.
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