| Target | |
|---|---|
| Synonyms | DF; ADN; PFD; ADIPSIN |
| Description | Recombinant human CFD Protein with C-terminal 10×His tag |
| Delivery | In Stock |
| Uniprot ID | P00746 |
| Expression Host | HEK293 |
| Tag | C-10×His tag |
| Molecular Characterization | CFD(Ile26-Ala253) 10×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 25.8 kDa after removal of the signal peptide. The apparent molecular mass of CFD-His is approximately 25-35 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CFD Protein, His Tag
Price:10μg $95.00 ; 50μg $330.00 ; 100μg $500.00
Product Data
Images
Figure 1. Human CFD Protein, His Tag on SDS-PAGE under reducing condition.
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