Name: Human CX3CR1-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120115

Tag	C-Flag&Strep Tag
Target	CX3CR1
Synonyms	CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28
Description	Human CX3CR1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P49238
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Molecular Weight	The human full length CX3CR1-Strep protein has a MW of 40.4 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS.
Usage	Research use only
Conjugate	Unconjugated

Human CX3CR1-Strep full length protein-synthetic nanodisc