Tag | C-Flag&Strep Tag |
---|---|
Target | |
Synonyms | C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; IL8R1; IL8RA; IL8RBA |
Description | Human CXCR1-Strep full length protein-synthetic nanodisc |
Delivery | 6~8weeks |
Uniprot ID | P25024 |
Expression Host | HEK293 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection |
Molecular Weight | The human full length CXCR1-Strep protein has a MW of 39.8 kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. |
Usage | Research use only |
Conjugate | Unconjugated |
Human CXCR1-Strep full length protein-synthetic nanodisc
Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00
Product Data
Images
Related Products
ECD Proteins
SKU: PME100820 Target: CXCR1
Price: 10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00
Monoclonal antibodies
SKU: DMC100470 Target: CXCR1
Application: Flow Cyt
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Full Length Transmembrane Proteins
SKU: FLP100091 Target: CXCR1
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Monoclonal antibodies
SKU: DMC100470B Target: CXCR1
Application: Flow Cyt
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00
Monoclonal antibodies
PE-conjugated Anti-CXCR1 antibody(DMC470); IgG1 Chimeric mAb
SKU: DMC100470P Target: CXCR1
Application: Flow Cyt
Price: 100 test $550.00