| Target | |
|---|---|
| Synonyms | ED1;EDA2 |
| Description | Recombinant Human EDA Protein with N-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q92838 |
| Expression Host | HEK293 |
| Tag | N-Human Fc Tag |
| Molecular Characterization | hFc(Glu99-Ala330) EDA(Ser160-Ser391) |
| Molecular Weight | The protein has a predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-EDA is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human EDA Protein, hFc Tag
Price: 10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00
Product Data
Images
Figure 1.Human EDA Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human EDA Protein, hFc Tag (PME100661) can bind Anti-EDA antibody(DMC388), IgG1 Chimeric mAb in a linear range of 3.20–80 ng/mL.
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