| Target | |
|---|---|
| Synonyms | ETB; ET-B; ETB1; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2 |
| Description | Recombinant human EDNRB Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P24530 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | EDNRB(Glu27-Lys101) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 34.2 kDa after removal of the signal peptide. The apparent molecular mass of EDNRB-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human EDNRB Protein, hFc Tag
Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00
Product Data
Images
Figure 1. Human EDNRB Protein, hFc Tag on SDS-PAGE under reducing condition.
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