| Target | |
|---|---|
| Synonyms | PGQTL2 |
| Description | Recombinant Human GIPR Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P48546 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | GIPR(Arg22-Gln138) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 39.6 kDa after removal of the signal peptide. The apparent molecular mass of GIPR-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human GIPR Protein, hFc Tag
Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00
Product Data
Images
Figure 1.Human GIPR Protein, hFc Tag on SDS-PAGE under reducing condition.
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