| Target | |
|---|---|
| Synonyms | TNFSF18;AITRL;TL6;hGITRL;GITR Ligand |
| Description | Recombinant human GITR Ligand protein with N-terminal mouse Fc and C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | Q9UNG2 |
| Expression Host | HEK293 |
| Tag | N-Mouse Fc and C-6×His Tag |
| Molecular Characterization | mFc(Pro99-Lys330) GITR Ligand(Gln50-Ser177) 6×His |
| Molecular Weight | The protein has a predicted molecular mass of 46-53 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human GITR Ligand Protein, mFc-His tag
Price: 10μg $85.00; 50μg $330.00 ; 100 μg $500.00
Product Data
Images
Figure 1.Human GITR Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.
Figure 2. Flow cytometry analysis with 1 μg/mL Human GITRL Protein, mFc-His tag (PME100020) on Expi293 cells transfected with human GITR (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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