Name: Human GLP2R-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120113

Tag	C-Flag&Strep Tag
Target	GLP2R
Synonyms	GLP-2-R; GLP-2R
Description	Human GLP2R-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	O95838
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length GLP2R-Strep protein has a MW of 63 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	A G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis.
Usage	Research use only
Conjugate	Unconjugated

Human GLP2R-Strep full length protein-synthetic nanodisc