Name: Human GPC6A full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100290

Tag	C-Flag Tag
Target	GPC6A
Synonyms	GPCR, bA86F4.3
Description	Human GPC6A full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q5T6X5
Expression Host	HEK293
Protein Families	Transmembrane,Druggable Genome,
Protein Pathways	N/A
Molecular Weight	The human full length GPC6A protein has a MW of 104.8kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain (summary by Pi et al., 2005 [PubMed 16199532]).[supplied by OMIM, Nov 2010]
Usage	Research use only
Conjugate	Unconjugated

Human GPC6A full length protein-synthetic nanodisc