Name: Human GPR35 full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100306

Tag	C-Flag Tag
Target	GPR35
Synonyms	G-protein coupled receptor 35; Kynurenic acid receptor (KYNA receptor)
Description	Human GPR35 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9HC97
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,
Molecular Weight	The human full length GPR35 protein has a MW of 34.1kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated

Human GPR35 full length protein-synthetic nanodisc