| Target | |
|---|---|
| Synonyms | GPRC5D |
| Description | Human GPRC5D full length protein on exosome |
| Delivery | In Stock |
| Uniprot ID | Q9NZD1 |
| Expression Host | HEK293 |
| Protein Families | GPCR |
| Protein Pathways | N/A |
| Molecular Weight | The human full length GPRC5D Protein has a MW of 38.6 kDa |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the G protein-coupled receptor family. Recent studies demonstrate that GPRC5D is expressed on malignant bone marrow plasma cells, whereas normal tissue expression is limited to the hair follicle. It may represent a potential target for effector-cell–mediated therapy to treat plasma-cell disorders like MM. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human GPRC5D full length protein-exo
Price: 50 μg $1200.00 ; 100 μg $1600.00
Product Data
Images
Figure1. Elisa plates were pre-coated with 0.5μg/per well purified human GPRC5D full length protein exosomes. Serial diluted anti-GPRC5D monoclonal antibody (DME100090) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-GPRC5D monoclonal antibody binding with GPRC5D exosomes is 41.99ng/ml.
Figure2. Nanoparticle Tracking Analysis of GPRC5D exosomes
Figure3. TEM image of GPRC5D exosomes
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