Name: Human HCRTR1-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120099

Tag	C-Flag&Strep Tag
Target	HCRTR1
Synonyms	ORXR1;OX1R;OXR1
Description	Human HCRTR1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	O43613
Expression Host	HEK293
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length HCRTR1-Strep protein has a MW of 47.5 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.
Usage	Research use only
Conjugate	Unconjugated

Human HCRTR1-Strep full length protein-synthetic nanodisc