| Target | |
|---|---|
| Synonyms | IL-13;NC30 |
| Description | Recombinant human IL13(35-146) protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P35225 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | IL13(Gly35-Asn146) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 38.4 kDa after removal of the signal peptide. The apparent molecular mass of IL13(35-146)-hFc is approximately 33-53 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human IL13(35-146) Protein, hFc Tag
Price: 10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00
Product Data
Images
Figure 1. Human IL13(35-146) Protein, hFc Tag on SDS-PAGE under reducing condition.
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