Name: Human KISSR full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100333

Tag	C-Flag Tag
Target	KISSR
Synonyms	AXOR12; CPPB1; GPR54; HH8; HOT7T175; KISS-1R
Description	Human KISSR full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	Q969F8
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length KISSR protein has a MW of 42.6 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.
Usage	Research use only
Conjugate	Unconjugated

Human KISSR full length protein-synthetic nanodisc