| Target | |
|---|---|
| Synonyms | CLEC8A;LOX1;LOXIN;SCARE1;SLOX1;OLR1 |
| Description | Recombinant Human LOX-1 Protein with N-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P78380 |
| Expression Host | HEK293 |
| Tag | N-Human Fc Tag |
| Molecular Characterization | hFc(Glu99-Ala330) LOX-1(Met58-Gln273) |
| Molecular Weight | The protein has a predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of hFc-LOX-1 is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human LOX-1 Protein, hFc Tag
Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00
Product Data
Images
Figure 1.Human LOX-1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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