Name: Human LT4R2 full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100342

Tag	C-Flag Tag
Target	LT4R2
Synonyms	BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9
Description	Human LT4R2 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9NPC1
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Other,Asthma,Autoimmune & Inflammatory Response,
Molecular Weight	The human full length LT4R2 protein has a MW of 37.9kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated

Human LT4R2 full length protein-synthetic nanodisc