| Target | |
|---|---|
| Synonyms | PYY4 |
| Description | Recombinant human NPY Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P01303 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | NPY(Tyr29-Trp97) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 34.2 kDa after removal of the signal peptide. The apparent molecular mass of NPY-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human NPY Protein, hFc Tag
Price: 10μg $90.00; 50μg $320.00 ; 100 μg $480.00
Product Data
Images
Figure 1. Human NPY Protein, hFc Tag on SDS-PAGE under reducing condition.
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