| Target | |
|---|---|
| Synonyms | PAI;PAI-1;SERPINE1;PLANH1 |
| Description | Recombinant Human PAI1 Protein with C-terminal 6XHis tag |
| Delivery | In Stock |
| Uniprot ID | P05121 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | PAI1(Val24-Pro402) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 43.6 kDa after removal of the signal peptide. The apparent molecular mass of PAI1-His is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human PAI1 Protein, His Tag
Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00
Product Data
Images
Figure 1.Human PAI1 Protein, His Tag on SDS-PAGE under reducing condition.
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