Human PLA2R1-Strep full length protein-synthetic nanodisc

Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00

SKU: FLP120147 Category: Full Length Transmembrane Proteins

Tag	C-Flag&Strep Tag
Target	PLA2R1
Synonyms	CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
Description	Human PLA2R1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q13018
Expression Host	HEK293
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length PLA2R1-Strep protein has a MW of 168.6 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
Usage	Research use only
Conjugate	Unconjugated