| Target | |
|---|---|
| Synonyms | EP4;EP4R |
| Description | Recombinant Human PTGER4 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P35408 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | PTGER4(Met1-Ser19) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 28.1 kDa after removal of the signal peptide. The apparent molecular mass of PTGER4-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human PTGER4 Protein, hFc Tag
Price: 10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00
Product Data
Images
Figure 1. Human PTGER4 Protein, hFc Tag on SDS-PAGE under reducing condition.
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