| Target | |
|---|---|
| Synonyms | SS-2-R; SS2-R; SS2R; SST2 |
| Description | Human SSTR2 full length protein membrane nanoparticles (MNPs) |
| Delivery | In Stock |
| Uniprot ID | P30874 |
| Expression Host | HEK293 |
| Protein Families | GPCR |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Molecular Weight | The human full length SSTR2 Protein has a MW of 41.2 kDa |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human SSTR2 full length protein-MNP
Price: 50 μg $1200.00 ; 100 μg $1600.00
Product Data
Images
Figure1. Elisa plates were pre-coated with 0.5μg/per well purified human SSTR2 full length membrane nanoparticles. Serial diluted anti-SSTR2 monoclonal antibody (BME100127) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-SSTR2 monoclonal antibody binding with SSTR2 full length membrane nanoparticles is 86.2ng/ml.
Figure2. FACS analysis of SSTR2 MNPs
A. Negative Control 1: SSTR2 full length membrane nanoparticles samples were stained only with Goat anti-human lgG 488 secondary antibody.
B. Negative Control 2: Control membrane nanoparticles samples were stained with anti-SSTR2 antibody (BME100127) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody.
C. Negative Control 3: SSTR2 full length membrane nanoparticles samples were stained with anti-GPRC5D antibody (an irrelevant antibody) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody.
D. SSTR2 full length membrane nanoparticles samples were stained with anti-SSTR2 antibody (BME100127) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody.
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