Name: Human TRFR full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100488

Tag	C-Flag Tag
Target	TRFR
Synonyms	CHNG7, TRH-R
Description	Human TRFR full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P34981
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,Peptide GPCRs,
Molecular Weight	The human full length TRFR protein has a MW of 45.1kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]
Usage	Research use only
Conjugate	Unconjugated

Human TRFR full length protein-synthetic nanodisc