Human TSHR-Strep full length protein-synthetic nanodisc

Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00

SKU: FLP120045 Category: Full Length Transmembrane Proteins

Tag	C-Flag&Strep Tag
Target	TSHR
Synonyms	CHNG1; hTSHR-I; LGR3
Description	Human TSHR-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P16473
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Autoimmune thyroid disease, Neuroactive ligand-receptor interaction
Molecular Weight	The human full length TSHR-Strep protein has a MW of 86.8 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism.
Usage	Research use only
Conjugate	Unconjugated