| Target | |
|---|---|
| Synonyms | LGR3; CHNG1; hTSHR-I |
| Description | Recombinant human TSHR(23-410) Protein with N-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P16473 |
| Expression Host | HEK293 |
| Tag | N-Human Fc tag |
| Molecular Characterization | hFc(Glu99-Ala330) TSHR(Gly23-Asp410) |
| Molecular Weight | The protein has a predicted molecular mass of 70.3 kDa after removal of the signal peptide. The apparent molecular mass of hFc-TSHR(23-410) is approximately 70-130 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human TSHR(23-410) Protein, hFc Tag
Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00
Product Data
Images
Figure 1. Human TSHR(23-410) Protein, hFc Tag on SDS-PAGE under reducing condition.
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