Name: Human TSPAN33-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120035

Tag	C-Flag&Strep Tag
Target	TSPAN33
Synonyms	PEN; PEN.; TSPAN-33
Description	Human TSPAN33-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q86UF1
Expression Host	HEK293
Protein Families	Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length TSPAN33-Strep protein has a MW of 31.5 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862).
Usage	Research use only
Conjugate	Unconjugated

Human TSPAN33-Strep full length protein-synthetic nanodisc