| Target | |
|---|---|
| Synonyms | Acvr2; ActrIIa; TactrII |
| Description | Recombinant mouse ACVR2A protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P27038 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | Mouse ACVR2A(Ala20-Pro135) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 39.6 kDa after removal of the signal peptide. The apparent molecular mass of mACVR2A-hFc is approximately 35-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Enables several functions, including BMP receptor activity; PDZ domain binding activity; and activin binding activity. Acts upstream of or within several processes, including Sertoli cell proliferation; copulation; and embryonic skeletal system development. Located in cell surface. Is expressed in several structures, including central nervous system; early conceptus; gonad; gut; and sensory organ. Used to study Weissenbacher-Zweymuller syndrome. Human ortholog(s) of this gene implicated in colon cancer. Orthologous to human ACVR2A (activin A receptor type 2A). [provided by Alliance of Genome Resources, Apr 2022] |
| Usage | Research use only |
Mouse ACVR2A Protein, hFc Tag
Price: 10μg $90.00 ; 50μg $320.00 ; 100μg $480.00
Product Data
Images
Figure 1. Mouse ACVR2A Protein, hFc Tag on SDS-PAGE under reducing condition.