| Target | |
|---|---|
| Synonyms | 6030411F23Rik;AU016588;B7h3;B7RP-2 |
| Description | Recombinant mouse B7-H3 protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q8VE98 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | Mouse B7-H3(Val29-Phe244) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 28.7 kDa after removal of the signal peptide.The apparent molecular mass of mB7-H3-hFc is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells.[UniProtKB/Swiss-Prot Function] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Mouse B7-H3 Protein, hFc Tag
Price: 10μg $72.00; 50μg $272.00; 100μg $409.00
Product Data
Images
Figure 1. Mouse B7-H3 Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Mouse B7-H3 Protein, hFc Tag (PME-M100008) can bind anti-B7-H3 monoclonal antibody DME100053 in a linear range of 3.2-400 ng/mL.
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