Target | |
---|---|
Synonyms | CD28;Tp44 |
Description | Recombinant mouse CD28 protein with C-terminal human Fc tag |
Delivery | In Stock |
Uniprot ID | P31041 |
Expression Host | HEK293 |
Tag | C-Human Fc Tag |
Molecular Characterization | Mouse CD28(Asn20-Lys149) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 41.2 kDa after removal of the signal peptide.The apparent molecular mass of mCD28-hFc is approximately 55-70 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.[UniProtKB/Swiss-Prot Function] |
Usage | Research use only |
Conjugate | Unconjugated |
Mouse CD28 Protein, hFc Tag
Price: 10μg $68.00; 50μg $259.00 ; 100 μg $389.00
Product Data
Images
Figure 1. Mouse CD28 Protein, hFc Tag on SDS-PAGE under reducing condition.
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