Target | |
---|---|
Synonyms | Ptprc;B220;L-CA;Ly-5;T200;CD45R;Lyt-4 |
Description | Recombinant mouse CD45 protein with C-terminal 6×His tag |
Delivery | In Stock |
Uniprot ID | P06800 |
Expression Host | HEK293 |
Tag | C-6×His Tag |
Molecular Characterization | Mouse CD45(Gln26-Lys566) 6×His tag |
Molecular Weight | The protein has a predicted molecular mass of 59.5 kDa after removal of the signal peptide. The apparent molecular mass of mCD45-His is approximately 130-250 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C). [provided by Alliance of Genome Resources, Apr 2022] |
Usage | Research use only |
Conjugate | Unconjugated |
Mouse CD45 Protein, His Tag
Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00
Product Data
Images
Figure 1. Mouse CD45 Protein, His Tag on SDS-PAGE under reducing condition.
Related Products
Monoclonal antibodies
SKU: DME100193 Target: CD45
Application: ELISA; Flow Cyt
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Biosimilar reference antibodies
SKU: BME100156P Target: CD45
Application: Flow Cyt
Price: 100 test $192.00
Monoclonal antibodies
SKU: DMC100725P Target: CD45
Application: Flow Cyt
Price: 100 test $550.00
Monoclonal antibodies
SKU: DME100193P Target: CD45
Application: Flow Cyt
Price: 100 test $550.00
DiSliceX
SKU: SLI100023 Target: CCR8, CD45, LGALS1
Application: Identification of immunohistochemical function
Price: 2 slides $129.00