| Target | |
|---|---|
| Synonyms | 9130415E20Rik;AA407862;AI848868;AW108519;B430305P08Rik;IAP;Itgp |
| Description | Recombinant mouse CD47 protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q61735 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | Mouse CD47(Gln19-Lys140) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 40.0 kDa after removal of the signal peptide.The apparent molecular mass of mCD47-hFc is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection (By similarity).[UniProtKB/Swiss-Prot Function] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Mouse CD47 Protein, hFc Tag
Price: 10μg $68.00; 50μg $259.00 ; 100 μg $389.00
Product Data
Images
Figure 1.Mouse CD47 Protein, hFc Tag on SDS-PAGE under reducing condition.
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