| Target | |
|---|---|
| Synonyms | Death receptor 5;MK;CD262 |
| Description | Recombinant mouse TNFRSF10B protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q9QZM4 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | Mouse TNFRSF10B(Asn53-Lys180) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 40.3 kDa after removal of the signal peptide. The apparent molecular mass of mTNFRSF10B-hFc is approximately 40-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Mouse TNFRSF10B Protein, hFc Tag
Price: 10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00
Product Data
Images
Figure 1. Mouse TNFRSF10B Protein, hFc Tag on SDS-PAGE under reducing condition.
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