Clone ID | DM101 |
---|---|
Target | |
Synonyms | CD40; Bp50; CDW40; MGC9013; TNFRSF5; p50 |
Host Species | Rabbit |
Description | PE-conjugated Anti-CD40 antibody(DM101); Rabbit mAb |
Delivery | 3-4 weeks |
Uniprot ID | P25942 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching; memory B cell development; and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand; which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation; and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-CD40 antibody(DM101); Rabbit mAb
Price: 100 test $550.00
Product Data
Images
Related Products
Biosimilar reference antibodies
SKU: BME100467 Target: CD40
Application: N/A
Price: 50μg $82.00 ; 100 μg $162.00
Biosimilar reference antibodies
SKU: BME100454 Target: CD40
Application: N/A
Price: 50μg $82.00 ; 100 μg $162.00
Biosimilar reference antibodies
SKU: BME100020B Target: CD40
Application: ELISA; Flow Cyt
Price: 50μg $99.00 ; 100 μg $199.00
Biosimilar reference antibodies
SKU: BME100401 Target: CD40
Application: N/A
Price: 50μg $82.00 ; 100 μg $162.00
Biosimilar reference antibodies
SKU: BME100636B Target: CD40
Application: N/A
Price: 50μg $99.00 ; 100 μg $199.00