Clone ID | 1A1 |
---|---|
Target | |
Synonyms | N.A. |
Host Species | Rabbit |
Description | PE-conjugated Anti-Dxd antibody(1A1); Rabbit mAb |
Delivery | 3-4 weeks |
Uniprot ID | N.A. |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | N.A. |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | Dxd is a potent anti-cancer drug, acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA, impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs), with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-Dxd antibody(1A1); Rabbit mAb
Price: 100 test $550.00
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