| Clone ID | 1E6 |
|---|---|
| Target | |
| Synonyms | N.A. |
| Host Species | Rabbit |
| Description | PE-conjugated Anti-Dxd antibody(1E6); Rabbit mAb |
| Delivery | 3-4 weeks |
| Uniprot ID | N.A. |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | N.A. |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Liquid，PBS with 0.05% Proclin300, 1% BSA |
| Storage & Shipping | Store at 2°C-8°C for 6 months |
| Background | Dxd is a potent anti-cancer drug, acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA, impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs), with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3. |
| Usage | Research use only |
| Conjugate | PE-conjugated |
PE-conjugated Anti-Dxd antibody(1E6); Rabbit mAb
Price: 100 test $550.00
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