Clone ID | DMC390 |
---|---|
Target | |
Synonyms | BETA-HFR; FBP; FBP:PL-1; FOLR1; FR-BETA; FR-P3; FRbeta |
Host Species | Rabbit |
Description | PE-conjugated Anti-FOLR2 antibody(DMC390); IgG1 Chimeric mAb |
Delivery | 3-4 weeks |
Uniprot ID | P14207 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | The protein encoded by this gene is a member of the folate receptor (FOLR) family; and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives; and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins; respectively. Although this protein was originally thought to be specific to placenta; it can also exist in other tissues; and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-FOLR2 antibody(DMC390); IgG1 Chimeric mAb
Price: 100 test $550.00
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