Clone ID | DM125 |
---|---|
Target | |
Synonyms | CD217;CDw217;IL-17RA;IL17R;CANDF5;hIL-17R |
Host Species | Rabbit |
Description | PE-conjugated Anti-IL17RA antibody(DM125); Rabbit mAb |
Delivery | 3-4 weeks |
Uniprot ID | Q96F46 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors; this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-IL17RA antibody(DM125); Rabbit mAb
Price: 100 test $550.00
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