Clone ID | DMC393 |
---|---|
Target | |
Synonyms | IL5Ra;CD125;IL-5 R alpha |
Host Species | Rabbit |
Description | PE-conjugated Anti-IL5RA antibody(DMC393); IgG1 Chimeric mAb |
Delivery | 3-4 weeks |
Uniprot ID | Q01344 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3); colony stimulating factor 2 (CSF2:GM-CSF); and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding; and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin); which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-IL5RA antibody(DMC393); IgG1 Chimeric mAb
Price: 100 test $550.00
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