Clone ID | DM157 |
---|---|
Target | |
Synonyms | MIC-A; PERB11.1 |
Host Species | Rabbit |
Description | PE-conjugated Anti-MICA antibody(DM157); Rabbit mAb |
Delivery | 3-4 weeks |
Uniprot ID | Q29983 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface; although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis; and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq; Jan 2014] |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-MICA antibody(DM157); Rabbit mAb
Price: 100 test $550.00
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