Clone ID | DMC298 |
---|---|
Target | |
Synonyms | CD159A; NKG2; NKG2A |
Host Species | Rabbit |
Description | PE-conjugated Anti-NKG2A antibody(DMC298); IgG1 Chimeric mAb |
Delivery | 3-4 weeks |
Uniprot ID | P26715 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family; also called NKG2 family; which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member; KLRD1:CD94; and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-NKG2A antibody(DMC298); IgG1 Chimeric mAb
Price: 100 test $550.00
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