Clone ID | 1G1 |
---|---|
Target | |
Synonyms | N.A. |
Host Species | Rabbit |
Description | PE-conjugated Anti-SN38 antibody(1G1); Rabbit mAb |
Delivery | 3-4 weeks |
Uniprot ID | N.A. |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | N.A. |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | SN38, a potent chemotherapeutic derived from irinotecan, plays a pivotal role in colorectal cancer treatment. As the active form of irinotecan, SN38 operates as an effective DNA topoisomerase I inhibitor, inducing cell death in cancer cells. Notably, SN38's potential is harnessed in Antibody-Drug Conjugates (ADCs), where it is delivered to tumor sites through innovative methods like liposomes and nanoparticles. This targeted approach enhances SN38's efficacy, emphasizing its crucial role in ADC-based strategies for precise and potent colorectal cancer therapy. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-SN38 antibody(1G1); Rabbit mAb
Price: 100 test $550.00
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